Anti-FAM189A1 antibody (bs-14767R)

Anti-FAM189A1 antibody

DATASHEET

Host:Rabbit

Target Protein:FAM189A1

IR:Immunogen Range:121-220/539

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:23359

Swiss Prot:O60320

Source:KLH conjugated synthetic peptide derived from human FAM189A1:121-220/539 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:FAM189A1 is a 539 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding FAM189A1 maps to human chromosome 15, which encodes more than 700 genes and is made up of approximately 106 million base pairs. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Horse
Rabbit
Guinea Pig
.

For research use only. Not intended for diagnostic or therapeutic use.