Anti-GPCR MRGE/GPCR GPR167 antibody
| 英文名称 | GPCR MRGE/GPCR GPR167 |
| 中文名称 | G蛋白偶联受体167抗体 |
| 别 名 | G protein coupled receptor 167; G-protein coupled receptor 167; GPR167; Mas related G protein coupled MRGE; MAS related GPR member E; Mas-related G-protein coupled receptor member E; MRGE; MRGPRE; MRGRE_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:GPCR MRGE/GPCR GPR167
IR:Immunogen Range:51-150/312
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:116534
Swiss Prot:Q86SM8
Source:KLH conjugated synthetic peptide derived from human GPCR MRGE/GPCR GPR167:51-150/312
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:MRGE is a 311 amino acid multi-pass membrane protein that acts as an orphan receptor and is though to influence nociceptor function. A member of the G-protein coupled receptor 1 family and MAS subfamily, MRGE is encoded by a gene that maps to human chromosome 11p15.4 and mouse chromosome 7 F5. Chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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