Anti-phospho-GRLF1 (Tyr1105) antibody (bs-16323R)

Anti-phospho-GRLF1 (Tyr1105) antibody

DATASHEET

Host:Rabbit

Target Protein:phospho-GRLF1 (Tyr1105)

IR:Immunogen Range:NI(p-Y)SV

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2909

Swiss Prot:Q9NRY4

Source:KLH conjugated synthesised phosphopeptide derived from human GRLF1 around the phosphorylation site of Tyr1105:NI(p-Y)SV 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.