Anti-GTF2H2C antibody
| 英文名称 | GTF2H2C |
| 中文名称 | 通用转录因子2H亚基2C抗体 |
| 别 名 | General transcription factor IIH polypeptide 2-like protein; General transcription factor IIH polypeptide 2C; General transcription factor IIH subunit 2-like protein; GTF2H2D; T2H2L_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:GTF2H2C
IR:Immunogen Range:101-200/395
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:728340
Swiss Prot:Q6P1K8
Source:KLH conjugated synthetic peptide derived from human GTF2H2C:101-200/395
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of 5 subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34 . Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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