Anti-KMT2A antibody
| 英文名称 | KMT2A |
| 中文名称 | 急性淋巴细胞性白血病1抗体 |
| 别 名 | Acute lymphocytic leukemia 1; ALL 1; ALL-1; ALL1; C-terminal cleavage product of 180 kDa; CXXC 7; CXXC-type zinc finger protein 7; CXXC7; HRX; HTRX 1; HTRX1; KMT2A; Lysine N-methyltransferase 2A; MLL 1A; Mll; MLL cleavage product C180; MLL1; MLL1_HUMAN; MLL1A; Myeloid/lymphoid or mixed lineage leukemia; N-terminal cleavage product of 320 kDa; p180; p320; Trithorax homolog; Trithorax homolog Drosophila; Trithorax like protein; Trithorax-like protein; TRX 1; TRX1; Zinc finger protein HRX. |
DATASHEET
Host:Rabbit
Target Protein:KMT2A
IR:Immunogen Range:3801-3969/3969
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4297
Swiss Prot:Q03164
Source:KLH conjugated synthetic peptide derived from human KMT2A:3801-3969/3969
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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