Anti-KIAA0427 antibody
英文名称 | KIAA0427 |
中文名称 | KIAA0427蛋白抗体 |
别 名 | CBP80/20-dependent translation initiation factor; ctif; CTIF_HUMAN; Gm672; Hypothetical protein LOC9811; Uncharacterized protein KIAA0427. |
DATASHEET
Host:Rabbit
Target Protein:KIAA0427
IR:Immunogen Range:101-200/598
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9811
Swiss Prot:O43310
Source:KLH conjugated synthetic peptide derived from human KIAA0427:101-200/598
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
.
For research use only. Not intended for diagnostic or therapeutic use.
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