Anti-SCFD1 antibody
| 英文名称 | SCFD1 |
| 中文名称 | 突触结合蛋白1样2抗体 |
| 别 名 | C14orf163; Chromosome 14 open reading frame 163; RA410; Scfd1; SCFD1_HUMAN; Sec1 family domain containing 1; Sec1 family domain-containing protein 1; SLY1; SLY1 homolog; Sly1p; STXBP1L2; Syntaxin binding protein 1 like 2; Syntaxin-binding protein 1-like 2; Vesicle transport related protein. |
DATASHEET
Host:Rabbit
Target Protein:SCFD1
IR:Immunogen Range:251-350/642
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:23256
Swiss Prot:Q8WVM8
Source:KLH conjugated synthetic peptide derived from human SCFD1:251-350/642
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SCFD1 is a 642 amino acid protein that belongs to the STXBP/unc-18/SEC1 family. Phosphorylated upon DNA damage, probably by Atm or ATR, SCFD1 is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi. The SCFD1 protein plays a role in SNARE-pin assembly and Golgi to ER retrograde transport via its interaction with COG4. The SCFD1 protein also binds Syntaxin 5. The SCFD1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, Drosophila, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana and rice, and maps to human chromosome 14q12. Deletion of a region of chromosome 14 that contains BF-1, PKC ? SCFD1, Cochlin and SG2NA genes, is responsible for a condition resulting in severe mental retardation, epilepsy, microcephaly and Rett-like features.
Size:100ul
Concentration:1mg/ml
Applications:
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant.
For research use only. Not intended for diagnostic or therapeutic use.
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