Anti-MCT14 antibody (bs-17714R)

Anti-MCT14 antibody

DATASHEET

Host:Rabbit

Target Protein:MCT14

IR:Immunogen Range:101-200/510

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:151473

Swiss Prot:Q7RTX9

Source:KLH conjugated synthetic peptide derived from human MCT14:101-200/510 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:MonocarboJNClates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboJNClate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT14 (monocarboJNClate transporter 14), also known as SLC16A14 (solute carrier family 16, member 14), is a 510 amino acid multi-pass membrane protein that belongs to the MCT family and functions as a proton-linked monocarboJNClate transporter, effectively catalyzing the rapid transport of monocarboJNClates across the membrane. Multiple isoforms of MCT14 exist due to alternative splicing events.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.