Anti-Mortality Factor 4 like 2 antibody
| 英文名称 | Mortality Factor 4 like 2 |
| 中文名称 | 死亡因子4样蛋白2抗体 |
| 别 名 | KIAA0026; MO4L2_HUMAN; MORF related gene X protein; MORF-related gene X protein; Morf4l2; MORFL2; Mortality factor 4 like protein 2; Mortality factor 4-like protein 2; MRGX; MSL3 2 protein; Protein MSL3-2; Transcription factor like protein MRGX; Transcription factor-like protein MRGX. |
DATASHEET
Host:Rabbit
Target Protein:Mortality Factor 4 like 2
IR:Immunogen Range:101-200/288
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9643
Swiss Prot:Q15014
Source:KLH conjugated synthetic peptide derived from human Mortality Factor 4 like 2:101-200/288
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Pig
Horse
Saccharomyces cerevisiae.
For research use only. Not intended for diagnostic or therapeutic use.
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