Anti-HSPC210/GSK3beta interaction protein antibody (bs-18090R)

Anti-HSPC210/GSK3beta interaction protein antibody

DATASHEET

Host:Rabbit

Target Protein:HSPC210/GSK3beta interaction protein

IR:Immunogen Range:1-100/139

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:51527

Swiss Prot:Q9P0R6

Source:KLH conjugated synthetic peptide derived from human GSKIP :1-100/139 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

Size:100ul

Concentration:1mg/ml

Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Cynomolgus Monkey.

For research use only. Not intended for diagnostic or therapeutic use.