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Anti-phospho-MCM2 (Ser139) antibody (bs-18261R)

Anti-phospho-MCM2 (Ser139) antibody (bs-18261R)

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Anti-phospho-MCM2 (Ser139) antibody

英文名称phospho-MCM2 (Ser139)
中文名称磷酸化MCM2蛋白抗体
别    名MCM2(phospho-Ser139); MCM2(phospho Ser139); MCM2 (phospho S139); p-MCM2(Ser139); p-MCM2(S139); MCM2 (phospho S139); p-MCM2 (phospho S139); BM28; CCNL 1; CCNL1; CDC like 1; CDC like-1; cdc19; CDCL 1; CDCL1; Cell devision cycle like 1; Cyclin like 1; cyclin like-1; D3S3194; DNA replication licensing factor MCM2; KIAA0030; MCM 2; MCM2; MCM2 minichromosome maintenance deficient 2 mitotin; MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae); MCM2 minichromosome maintenance deficient 2, mitotin; MCM2_HUMAN; MCM2_MOUSE; MGC10606; Minichromosome maintenance complex component 2; Minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance deficient 2 mitotin; Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; Mitotin; Nuclear protein BM28; OTTHUMP00000216047; OTTHUMP00000216050.

DATASHEET

Host:Rabbit

Target Protein:phospho-MCM2 (Ser139)

IR:Immunogen Range:YD(p-S)DE

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:4171

Swiss Prot:P49736

Source:KLH conjugated synthesised phosphopeptide derived from human MCM2 around the phosphorylation site of Ser139:YD(p-S)DE 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

Size:100ul

Concentration:1mg/ml

Applications:

Cross Reactive Species:Human
Rat
Dog
Pig
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

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