Anti-LRP2BP antibody (bs-18363R)

Anti-LRP2BP antibody

DATASHEET

Host:Rabbit

Target Protein:LRP2BP

IR:Immunogen Range:101-200/347

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:55805

Swiss Prot:Q9P2M1

Source:KLH conjugated synthetic peptide derived from human LRP2BP:101-200/347 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:?LRP2BP is a 347 amino acid protein that contains one TPR repeat and six Sel1-like repeats. Localized to the plasma membrane and throughout the cytoplasm, LRP2BP interacts with megalin (also known as LRP2) and, via this interaction, is thought to regulate megalin function. Specifically, LRP2BP acts as a scaffold protein that, through its TPR motifs, assists in the sequestration and/or the release of transcription factors that influence megalin’s affects on endocytosis and hormone release. LRP2BP is expressed in colon, testis, small intestine and blood leukocytes, as well as in pancreatic adenocarcinoma cells, suggesting a possible role for LRP2BP in carcinogenesis. Two isoforms of LRP2BP exist due to alternative splicing events.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.