Anti-Meprin beta antibody
| 英文名称 | Meprin beta |
| 中文名称 | 苯甲酸肽水解酶β抗体 |
| 别 名 | Endopeptidase 2; kinase splitting membranal proteinase; KSMP; Meprin 1 beta subunit; Meprin A beta; Meprin A beta subunit precursor; N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit; PABA peptide hydrolase; PPH beta. |
DATASHEET
Host:Rabbit
Target Protein:Meprin beta
IR:Immunogen Range:151-250/701
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4225
Swiss Prot:Q16820
Source:KLH conjugated synthetic peptide derived from human Meprin beta:151-250/701
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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