Anti-MXI1 antibody
| 英文名称 | MXI1 |
| 中文名称 | MXI1蛋白抗体 |
| 别 名 | bHLHc11; Class C basic helix-loop-helix protein 11; MAD 2; MAD2; MAX dimerization protein 2; MAX interacting protein 1; Max interactor 1; Max related transcription factor; MAX-interacting protein 1; MGC43220; MXD 2; MXD2; MXI 1; MXI; mxi1; MXI1 protein; MXI1_HUMAN; Protein MXI1. |
DATASHEET
Host:Rabbit
Target Protein:MXI1
IR:Immunogen Range:1-100/228
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4601
Swiss Prot:P50539
Source:KLH conjugated synthetic peptide derived from human MXI1:1-100/228
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
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