Anti-NFRKB antibody
英文名称 | NFRKB |
中文名称 | DNA结合蛋白κB抗体 |
别 名 | A530090G11Rik; DKFZp547B2013; DNA binding protein R kappa B; INO80 complex subunit G; INO80G; Nuclear factor related to kappa B binding protein; Nuclear factor related to kappaB binding protein. |
DATASHEET
Host:Rabbit
Target Protein:NFRKB
IR:Immunogen Range:471-570/1299
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4798
Swiss Prot:Q6P4R8
Source:KLH conjugated synthetic peptide derived from human NFRKB:471-570/1299
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:DNA-binding protein R kappa-B, is a nuclear protein that binds to the DNA consensus sequence 5'-GGGGAATCTCC-3' of NF kappa B. Binding of NFR kappa B is thought to regulate IL-2R alpha (interleukin-2 receptor alpha-chain) gene expression, a critical step in T-cell activation. NFR kappa B exists as 3 isoforms due to alternative splicing and is expressed primarily in the brain, liver, spleen, testis and thymus NFR kappa B gene expression is amplified in acute myeloid leukemia, suggesting a possible role in carcinogenesis.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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