Anti-NLRP8 antibody
| 英文名称 | NLRP8 |
| 中文名称 | NLRP8蛋白抗体 |
| 别 名 | CLR19.2; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 8; NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NALP8; NALP8_HUMAN; NLR family, pyrin domain containing 8; NLRP8; NOD16; Nucleotide-binding oligomerization domain protein 16; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8; PAN4; PYRIN and NACHT-containing protein 4; PYRIN domain- and NACHT domain-containing protein 4. |
DATASHEET
Host:Rabbit
Target Protein:NLRP8
IR:Immunogen Range:101-200/1048
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:126205
Swiss Prot:Q86W28
Source:KLH conjugated synthetic peptide derived from human NLRP8:101-200/1048
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP8, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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