Anti-PRPF38A antibody (bs-19403R)

Anti-PRPF38A antibody

DATASHEET

Host:Rabbit

Target Protein:PRPF38A

IR:Immunogen Range:101-200/312

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:84950

Swiss Prot:Q8NAV1

Source:KLH conjugated synthetic peptide derived from human PRPF38A:101-200/312 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:HPRP18 is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Zebrafish
Sheep
Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis .

For research use only. Not intended for diagnostic or therapeutic use.