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Anti-PDE6A antibody (bs-12584R)

Anti-PDE6A antibody (bs-12584R)

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Anti-PDE6A antibody

英文名称PDE6A
中文名称磷酸二酯酶6α抗体
别    名PDE6 alpha; 5''-cyclic phosphodiesterase subunit alpha; CGPR A; GMP PDE alpha; GMP-PDE alpha; PDE 6 alpha; PDE 6A; PDE V B1; PDE V-B1; PDE6A; PDE6A_HUMAN; PDEA; Phosphodiesterase 6 alpha; Phosphodiesterase 6A alpha subunit; Phosphodiesterase 6A cGMP specific rod alpha; Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha; Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit; Rod cGMP-specific 3''. 

DATASHEET

Host:Rabbit

Target Protein:PDE6A

IR:Immunogen Range:101-200/860

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5145

Swiss Prot:P16499

Source:KLH conjugated synthetic peptide derived from human PDE6A:101-200/860 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.

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