Anti-phospho-PLB (Ser16+Thr17) antibody
| 英文名称 | phospho-PLB (Ser16+Thr17) |
| 中文名称 | 磷酸化心脏磷蛋白(Ser16+Thr17)抗体 |
| 别 名 | Phospholamban (phospho S16+T17); p-Phospholamban (phospho S16+T17); Phospho-Phospholamban (Ser16/Thr17); phospholamban(phospho Ser16+Thr17); p-PLB(S16+T17); Cardiac phospholamban; CMD1P; PLB; PLN; PPLA_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:phospho-PLB (Ser16+Thr17)
IR:Immunogen Range:RA(p-S)(p-T)IE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5350
Swiss Prot:P26678
Source:KLH conjugated synthesised phosphopeptide derived from human PLB around the phosphorylation site of Ser16+Thr17:RA(p-S)(p-T)IE
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
好评度