Anti-Slc26a5 antibody
| 英文名称 | Slc26a5 |
| 中文名称 | 感觉神经性耳聋常染色体隐性遗传61抗体 |
| 别 名 | Prestin; Deafness neurosensory autosomal recessive 61; DFNB 61; DFNB61; MGC118886; MGC118887; MGC118888; MGC118889; PRES; Prestin (motor protein); Prestin; S26A5_HUMAN; SLC26A5; Solute carrier family 26 member 5 (prestin); Solute carrier family 26 member 5. |
DATASHEET
Host:Rabbit
Target Protein:Slc26a5
IR:Immunogen Range:201-300/744
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:375611
Swiss Prot:P58743
Source:KLH conjugated synthetic peptide derived from human Slc26a5:201-300/744
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Size:100ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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