Anti-Cyclin T1 antibody
| 英文名称 | Cyclin T1 |
| 中文名称 | 周期素T1抗体 |
| 别 名 | CCN T1; CCNT; CCNT 1; CCNT1; CCNT1_HUMAN; CDK9 associated C type protein; Cyc T1; Cyclin C related protein; cyclin T; cyclin T1; Cyclin T1b; Cyclin-T; cyclin-T1; CYCT 1; cycT1; HIVE1; Human immunodeficiency virus 1 expression; Human immunodeficiency virus type 1 (HIV 1) expression (elevated) 1; pTEFb subunit; Subunit of positive elongation transcription factor b. |
DATASHEET
Host:Rabbit
Target Protein:Cyclin T1
IR:Immunogen Range:451-550/726
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:904
Swiss Prot:O60563
Source:KLH conjugated synthetic peptide derived from human Cyclin T1:451-550/726
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboJNC-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
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