Anti-DUSP6 antibody
英文名称 | DUSP6 |
中文名称 | 双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体 |
别 名 | Dual specificity phosphatase 6; Dual specificity phosphatase 6 isoform a; Dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; DUS6_HUMAN; DUSP 6; DUSP 6a; Dusp6; DUSP6a; MAP kinase phosphatase 3; Mitogen activated protein kinase phosphatase 3; Mitogen-activated protein kinase phosphatase 3; MKP 3; MKP-3; MKP3; PYST 1; PYST1; Serine/threonine specific protein phosphatase. |
DATASHEET
Host:Rabbit
Target Protein:DUSP6
IR:Immunogen Range:51-150/381
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1848
Swiss Prot:Q16828
Source:KLH conjugated synthetic peptide derived from human DUSP6:51-150/381
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
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