Ac-IETD-pNA
| 英文名称 | Ac-IETD-pNA |
| 中文名称 | Caspase 8显色底物 (Ac-IETD-pNA) |
| 别 名 | N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide; Caspase-8 Substrate; N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase-8 Substrate(Chromogenic); N-Acetyl-Ile-Glu-Thr-Asp-pNA; Caspase Substrate, chromogenic; |
| 保存条件 | Store at -20 °C for one year. |
| 产品介绍 | Chromogenic substrate for caspase 8 and granzyme B. IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 纯度：>95%(HPLC) 分子式：C34H37N9O11 分子量：747.7 序列：N-Acetyl-Ile-Glu-Thr-Asp-p-Nitroanilide 来源：合成 外观/性状：Lyophilized Yellow Powder 溶解性：Soluble in DMSO 敏感性：对光敏感 简介：Ac-IETD-pNA是Caspase 8的底物，被剪切后可产生黄色的pNA (p-nitroaniline)，pNA在405nm附近有强吸收，可以通过测定吸光度来检测Caspase 8的活性。 用途：Chromogenic substrate for caspase-1, -4 and -5. Most potent for caspase-1. ; max of pNA 400nm. 配方：20mM in DMSO: 5mg加入0.39ml DMSO，或每12.77mg加入1ml DMSO，配制成20mM溶液。 |
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