Anti-Phospho-Rb (Ser807) antibody
| 英文名称 | Phospho-Rb (Ser807) |
| 中文名称 | 磷酸化视网膜母细胞瘤相关蛋白1重组兔单克隆抗体 |
| 别 名 | Rb(S807); Rb(Phospho-Ser807); Rb (phospho S807); p-Rb (phospho S807); p105-Rb (phospho-Ser807 + Ser811); p105-Rb (phospho Ser807 + Ser811); Rb (phospho S811); p-Rb (phospho S811); p-Rb (Ser807 + Ser811); OSRC; P105 RB; P105RB; PP105; PP110; pRb; RB 1; RB1; RB1 protein; Retinoblastoma 1 (including osteosarcoma); Retinoblastoma 1; Retinoblastoma associated protein; Retinoblastoma related osteosarcoma; Retinoblastoma susceptibility gene; Including osteosarcoma; RB_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-Rb (Ser807)
IR:Immunogen Range:YI(p-S)PLK
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:5925
Swiss Prot:P06400
Source:KLH conjugated Synthesised phosphopeptide derived from human Rb around the phosphorylation site of Ser807:YI(p-S)PLK
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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