Anti-PI 3 Kinase p85 alpha antibody
| 英文名称 | PI 3 Kinase p85 alpha |
| 中文名称 | 磷脂酰肌醇激酶单克隆抗体 |
| 别 名 | PI3-kinase p85 subunit alpha; PI3K p85; GRB1; p50 alpha; p55 alpha; p85 alpha; p85; Phosphatidylinositol 3 kinase associated p85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase regulatory alpha subunit; Phosphoinositide 3 kinase regulatory subunit polypeptide 1 (p85 alpha); PI3 kinase p85 alpha subunit; PI3 kinase p85 subunit alpha; PI3K; PIK3R1; PtdIns 3 kinase p85 alpha; SH3_PI3K_p85alpha; P85A_HUMAN; PI 3-kinase p85α; PI 3-kinase p85 α; PI 3-kinase p85-α. |
DATASHEET
Host:Mouse
Target Protein:PI 3 Kinase p85 alpha
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:5295
Swiss Prot:P27986
Source:Recombinant human PI3-kinase p85 subunit alpha protein, around 600-700aa:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:1000-2000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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