Anti-STAT2 antibody
英文名称 | STAT2 |
中文名称 | 信号转导和转录激活因子2重组兔单克隆抗体 |
别 名 | signal transducers and activators of transduction2; Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator; ISGF3; P113; signal transducer and activator of transcription 2 113kD; STAT113; STAT2_HUMAN; p113. |
DATASHEET
Host:Rabbit
Target Protein:STAT2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:6773
Swiss Prot:P52630
Source:Recombinant human STAT2 protein (1-100aa):
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:400-800)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
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