Anti-Cardiac Troponin I-C (cTnC) antibody
英文名称 | Cardiac Troponin I-C (cTnC) |
中文名称 | 心肌肌钙蛋白单克隆抗体 |
别 名 | troponin I type 3 (cardiac); Cardiac troponin I; Troponin I, cardiac muscle; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC-1; TNNC1; TNNI3; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; Troponin I; TNNI3_HUMAN. |
研究领域 | 心血管 免疫学 |
抗体来源 | Mouse |
克隆类型 | Monoclonal |
克 隆 号 | 5D12K |
交叉反应 | Human, |
产品应用 | ELISA=1:5000-10000 GICA=1:20-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 23kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | >1mg/ml |
免 疫 原 | Recombinant human Cardiac Troponin I-C: |
亚 型 | IgG1 |
纯化方法 | affinity purified by Protein G |
储 存 液 | 0.01M PBS(pH7.4) with 0.03% Proclin300. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
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