Anti-Huntingtin antibody
| 英文名称 | Huntingtin |
| 中文名称 | 神经性舞蹈病蛋白重组兔单克隆抗体 |
| 别 名 | HD; HD protein; HD_HUMAN; HDH; HTT; Huntingtin; HUNTINGTON CHOREA; Huntington disease protein; Huntington's disease protein homolog; IT 15; IT15; OTTMUSP00000026909; ZHD; AI256365; C430023I11Rik. |
DATASHEET
Host:Rabbit
Target Protein:Huntingtin
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:3064
Swiss Prot:P42858
Source:KLH conjugated synthetic peptide derived from human Huntingtin:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Huntingtin is a protein that contains a polyglutamine region. When the number of glutamine repeats exceeds 35, the gene encodes a version of Huntingtin that leads to Huntington’s disease (HD). When the polyglutamine stretch is mutated, Huntingtin acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. Loss of Huntingtin activity is unlikely to be the cause of HD, and it has been proposed that the expanded glutamine repeat region may induce an abnormal interaction between the mutant protein and other cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH) and HIP1.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:200-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:20-100)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
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