所有产品科研使用,仅用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务
Recombinant Human Fetuin A Protein is a major plasma protein and a member of the cystatin superfamily of protease inhibitors. Human Fetuin A is expressed by hepatocytes, the principal cell source, and by monocyte/macrophages. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. It is a negative acute-phase protein with normal circulating levels in adults (300-600 μg/mL), which fall significantly (30-50%) during injury and infection. Human Fetuin A inhibits both insulin receptor autophosphorylation and undesirable calcification . It also can act as a natural antagonist against specific TGF-β and BMP signaling proteins.
Expression host is Human HEK293 cells
动物 A (mg/kg) = 动物 B (mg/kg) × | 动物 B的Km系数 |
动物 A的Km系数 |
例如,依据体表面积折算法,将化合物用于小鼠的剂量20 mg/kg 换算成大鼠的剂量,需要将20 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到化合物用于大鼠的等效剂量为10 mg/kg。
分子量 | |
分子式 | |
CAS号 | |
纯度 | ≥95%, Endotoxin ≤0.01EU/ug |
溶解性(25°C) | Water Saline PBS |
储存和运输条件 | 2-8°C, dry, sealed 常温运输及临时存放 |
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